Fermented food products in the era of globalization: tradition meets biotechnology innovations

Omics tools offer the opportunity to characterize and track traditional food and industrial fermentation. Bioinformatics, through machine learning, and other advanced statistical approaches, able to parse the fermentation process and predict the evolution and metabolic yields of food microbial ecosystems. By assembling a microbial-made consortival, the progress of biotechnology will also be able to increase the nutritional value and organoleptic characteristics of fermented food, preserve, at the same time, the potential of microbial consortiums autochthonous and metabolic pathways, which are difficult to reproduce. Preserving traditional methods contribute to protecting hidden values ​​from local biodiversity, and exploiting their potential in industrial processes with the final objectives guaranteeing food security and safety, even in developing countries.

Biotechnology and therapeutic-based therapeutial strategies for age-related macular degeneration. Part I: Biomaterial-based drug delivery device

The age-related macular degeneration (AMD) is a chronic neurodegenerative eye disease that can be treated in the latest, and the main causes of blindness in more than 65 years. It is characterized by slow developments and the existence of many factors, highlights associated with diet, genetic inheritance and environmental conditions, present at each stage of the disease. The current therapeutic approach, mainly consists of administration of intraocular drugs, only used to eliminate symptoms and / or to exceed the development of the disease.

Furthermore, they are too simple and ignore the complexity of the disease and large differences in the symptomatology between patients. Due to the broad impact of AMD and the absence of current clinical solutions, the development of a biomaterial-based approach for subjective and controlled therapeutic and biomolecular delivery represents the main challenges for the defeat of neurodegenerative diseases.

Here we present a critical review of the AMD therapy approach that is available and in development, from biomaterials and biotechnology perspectives. We highlight the benefits and limitations and we estimate the upcoming alternatives based on new biomaterials and biotechnology methods. In the first part we expose the physiological and clinical aspects of the disease, focusing on several factors that gave the origin of interference and highlight the contribution of these factors to the trigger of every step of the disease. Then we analyze available and in the development of biomaterial-based drug delivery devices (DDD), taking into account the characteristics of anatomy and functional from a healthy and sick retinal tissue.

RCSB Protein Data Banks: Strong new tools to explore biological 3D macromolecular structures for basic and applied research and applied in fundamental biology, biomedical, biotechnology, bioengineering and energy science

Collaboratory Research for Bioinformatics Structural Protein Data Bank (RCSB GDP), US Data Center for Global GDP Archives and Founder Members of the World Worldwide Protein Data Partners, serving tens of thousands of data deposits in America and Oceania and making 3D macromolecular structure data available at no cost and without Limitations to millions of users of RCSB.org worldwide, including> 660,000 educators, students and community members who want to know using pdb101.rcsb.org.

PDB data deposits include structural biologists using macromolecular crystallography, nuclear magnetic resonance spectroscopy, 3D electron microscope and micro-electron diffraction. Consumer GDP data that accesses our web portals includes researchers, educators and students who study fundamental biology, biomedical, biotechnology, bioengineering and energy science. Over the past 2 years, the RCSB GDP web portal which focuses on research (RCSB.org) has experienced a complete redesign, allowing increased searches with full Boolean operator logic and easier access to integrated GDP data with> 40 external biodata resources. New features and resources are explained in detail using examples that show the structure of SARS-COV-2 protein which was recently released and host cell protein relevant to understanding and overcoming Global Pandemics Covid-19.

Holistic Approach Banking Cell NGNokan Swiss Fetus: Optimizing Safe and Sustainable Substrate for Regenerative Treatment and Biotechnology

The iterative safety, quality and optimization driven by the selection of therapeutic cell sources has formed the basic rock in the core development for primary fetal progenitor cell therapy (FPC) in Switzerland for three decades. Pragmatic adjustable fetus transplant program is designed as a direct workflow for network procurement, maximizing traceability, safety, consistency, and robustness of cultured progeni cellular materials. The standardization of intact cell bioprocess has provided adequate insight into adequate conjugation of modern biotechnology progress with the current legislative, ethical and regulatory framework.

Pioneer translational progress in regenerative skin and musculoskeletal treatment continuously shows the potential for FPC therapy. Extensive technical and clinical actions were collected by managing pediatric burns and geriatric ulcers in Switzerland. The simultaneous industrial transposition of Dermal FPC banks, after good manufacturing practice, shows the wide potential of their therapeutic value. Furthermore, in Extenso, the exponential revalorization of Swiss FPC technology can be achieved through an integrative update of the model framework. Consideration of longitudinal and transverse aspects of simultaneous fetal network differential processing allows a better understanding of potential power expansion – unlimited in multi-tiered main FPC banks.

10x Taq Buffer (NH4)2SO4
PCRB55	Bio Basic	4x1.5ml, 6ml	EUR 70.44

Taq Buffer with NH42SO4 10X
11170073-1	Bio-WORLD	5x1 mL	EUR 33.45

Taq Buffer without Detergent 10X
11170076-1	Bio-WORLD	5x1 ml	EUR 33.45

DiaStar Taq Reaction Buffer 10X
11170005-1	Bio-WORLD	5 mL	Ask for price

Taq Buffer with KCl and MGCl2 10X
11170072-1	Bio-WORLD	5x1 mL	EUR 33.33

Taq Buffer with NH42SO4 and MgCl2 10X
11170074-1	Bio-WORLD	5x1 ml	EUR 33.45

10x Taq Buffer with (NH4)2SO4 1.8 ml
BA00152	Bioatlas	1.8ml	EUR 66
Description: High purity buffer for various PCR applications.

e-Taq Reaction Buffer 10X
11170006-1	Bio-WORLD	5 mL	Ask for price

F-Taq Reaction Buffer 10X
11170007-1	Bio-WORLD	5 mL	Ask for price
Description: FastStart Taq DNA Polymerase

h-Taq Reaction Buffer 10X
11170029-1	Bio-WORLD	5 mL	Ask for price

10X Taq Buffer with KCl - 4 x 1.25 mL
THB38	Westburg	each	EUR 21.8

10X Taq Buffer without Detergent - 4 x 1.25 mL
THB55	Westburg	each	EUR 21.8

10X Taq Buffer with (NH4)2SO4 - 4 x 1.25 mL
THB33	Westburg	each	EUR 22.35

Taq DNA Polymerase with 10X Reaction (MgCl2) Buffer
MBS308022-1000Units	MyBiosource	1000Units	EUR 225

Taq DNA Polymerase with 10X Reaction (MgCl2) Buffer
MBS308022-100Units	MyBiosource	100Units	EUR 135

Taq DNA Polymerase with 10X Reaction (MgCl2) Buffer
MBS308022-500Units	MyBiosource	500Units	EUR 170

Taq DNA Polymerase with 10X Reaction (No MgCl2) Buffer
MBS308028-1000Units	MyBiosource	1000Units	EUR 225

Taq DNA Polymerase with 10X Reaction (No MgCl2) Buffer
MBS308028-100Units	MyBiosource	100Units	EUR 120

Taq DNA Polymerase with 10X Reaction (No MgCl2) Buffer
MBS308028-500Units	MyBiosource	500Units	EUR 170

10X Taq Buffer with KCl and 15 mM MgCl2 - 4 x 1.25 mL
THB16	Westburg	each	EUR 17.44

10X Taq Buffer with (NH4)2SO4 and 20 mM MgCl2 - 4 x 1.25 mL
THB34	Westburg	each	EUR 21.8

TT Buffer 10X
21420025-1	Bio-WORLD	1 L	EUR 106.79

TT Buffer 10X
21420025-2	Bio-WORLD	500 mL	EUR 51.93

TE Buffer, 10x
TBS5010	Tribioscience	1L	EUR 45

STE Buffer 10X
10530015-1	Bio-WORLD	1 L	EUR 64.77

STE Buffer 10X
10530015-2	Bio-WORLD	4 L	EUR 179.69

TBS Buffer 10X
42020056-1	Bio-WORLD	500 mL	EUR 36.58

TBS Buffer 10X
42020056-2	Bio-WORLD	1 L	EUR 53.42

TBS Buffer 10X
42020056-3	Bio-WORLD	4 L	EUR 183.56

TBS Buffer 10X
42020056-4	Bio-WORLD	6 L	EUR 275.16

TPE Buffer 10X
42020124-1	Bio-WORLD	1 L	EUR 51.22

TPE Buffer 10X
42020124-2	Bio-WORLD	2 L	EUR 82.23

TPE Buffer 10X
42020124-3	Bio-WORLD	4 L	EUR 143.68

TPE Buffer 10X
42020124-4	Bio-WORLD	500 mL	EUR 28.24

DEA Buffer 10X
40420000-1	Bio-WORLD	50 mL	EUR 36.73
Description: Diethanolamine Buffer Concentrate

DEA Buffer 10X
40420000-2	Bio-WORLD	100 mL	EUR 67.11
Description: Diethanolamine Buffer Concentrate

TTE Buffer 10X
21420034-1	Bio-WORLD	500 mL	EUR 42.73

TTE Buffer 10X
21420034-2	Bio-WORLD	1 L	EUR 74.78

TTE Buffer 10X
21420034-3	Bio-WORLD	4 L	EUR 174.19

EIA Buffer 10X
22040030-1	Bio-WORLD	50 mL	EUR 35.74

EIA Buffer 10X
22040030-2	Bio-WORLD	100 mL	EUR 58.1

NH4 Buffer, 10x
BIO-37025	Bioline	3 x 1.2ml	Ask for price

NH4 Buffer (10X)
abx461049-1096tests	Abbexa	10 × 96 tests	Ask for price

NH4 Buffer (10X)
abx461049-596tests	Abbexa	5 × 96 tests	Ask for price

NH4 Buffer (10X)
abx461049-96tests	Abbexa	96 tests	EUR 387.5

TAE Buffer, 10x
TBS5006	Tribioscience	1L	EUR 24

TBE Buffer, 10x
TBS5007	Tribioscience	1L	EUR 24

TBS Buffer, 10x
TBS5024	Tribioscience	1L	EUR 45

TBS Buffer, 10X
T8057-100	GenDepot	1L	EUR 54

TBS Buffer, 10X
T8057-105	GenDepot	5x1L	EUR 185

RIPA Buffer(10x)
08714-04	NACALAI TESQUE	1SET	EUR 98

MESA Buffer 10X
41320060-1	Bio-WORLD	100 mL	EUR 60.61

MESA Buffer 10X
41320060-2	Bio-WORLD	250 mL	EUR 95.76

MESA Buffer 10X
41320060-3	Bio-WORLD	500 mL	EUR 160.33

MESA Buffer 10X
41320060-4	Bio-WORLD	1 L	EUR 268.06

TBST Buffer (10x)
MBS2557004-100mL	MyBiosource	100mL	EUR 80

TBST Buffer (10x)
MBS2557004-200mL	MyBiosource	200mL	EUR 85

TBST Buffer (10x)
MBS2557004-500mL	MyBiosource	500mL	EUR 90

TBST Buffer (10x)
MBS2557004-5x500mL	MyBiosource	5x500mL	EUR 365

TBST Buffer, 10x
TBS5008	Tribioscience	1L	EUR 45

Running Buffer 10X
44040002-1	Bio-WORLD	100 mL	EUR 22.1

Running Buffer 10X
44040002-2	Bio-WORLD	250 mL	EUR 44.33

Running Buffer 10X
44040002-3	Bio-WORLD	500 mL	EUR 63.5

Running Buffer 10X
44040002-4	Bio-WORLD	1 L	EUR 106.79

Taq DNA Polymerase with dNTP Mix, 10X Mg free Buffer and 25mM MgCl2
11140016-1	Bio-WORLD	500 Unit (s)	EUR 132.93

Taq DNA Polymerase with dNTP Mix, 10X Mg free Buffer and 25mM MgCl2
11140016-2	Bio-WORLD	2500 Unit (s)	EUR 601.37

Taq DNA Polymerase with dNTP Mix, 10X Mg free Buffer and 25mM MgCl2
11140016-3	Bio-WORLD	5000 Unit (s)	EUR 1119.45

10X TA Buffer
IBS-BT001	iNtRON Biotechnology Inc	1L	EUR 42

10X TE Buffer
IBS-BT009	iNtRON Biotechnology Inc	500 mL	EUR 56

10X DEA Buffer
IBS-BD002	iNtRON Biotechnology Inc	100 mL	EUR 49

10X PCR Buffer.
IBS-BP060	iNtRON Biotechnology Inc	5 mL	EUR 42

10X STE Buffer
IBS-BS043	iNtRON Biotechnology Inc	500 mL	EUR 28

10X TAE Buffer
IBS-BT002-2	iNtRON Biotechnology Inc	1L	EUR 28

10X TAE Buffer
IBS-BT002-2a	iNtRON Biotechnology Inc	500 mL	EUR 21

10X TBS Buffer
IBS-BT005	iNtRON Biotechnology Inc	1L	EUR 49

10X TEN buffer
IBS-BT032	iNtRON Biotechnology Inc	500 mL	EUR 37.1

10X TAE Buffer
T8048-101	GenDepot	1L	EUR 32

Transmembrane Buffer (10x)
MBS2557003-100mL	MyBiosource	100mL	EUR 80

Transmembrane Buffer (10x)
MBS2557003-200mL	MyBiosource	200mL	EUR 85

Transmembrane Buffer (10x)
MBS2557003-500mL	MyBiosource	500mL	EUR 90

Transmembrane Buffer (10x)
MBS2557003-5x500mL	MyBiosource	5x500mL	EUR 365

10X Wash Buffer
DS0230-100ML	EWC Diagnostics	1 unit	EUR 2.57
Description: 10X Wash Buffer

10X Wash Buffer
DS0230-500ML	EWC Diagnostics	1 unit	EUR 11.68
Description: 10X Wash Buffer

10X MOPS Buffer
IBS-BM003	iNtRON Biotechnology Inc	1L	EUR 98

10X MOPS Buffer
M1057-050	GenDepot	500ml	EUR 193.2

10X MOPS Buffer
M1057-100	GenDepot	2X500ml	EUR 262.8

Electrophoresis Buffer (10x)
MBS2557002-100mL	MyBiosource	100mL	EUR 85

Electrophoresis Buffer (10x)
MBS2557002-200mL	MyBiosource	200mL	EUR 90

Electrophoresis Buffer (10x)
MBS2557002-500mL	MyBiosource	500mL	EUR 95

Electrophoresis Buffer (10x)
MBS2557002-5x500mL	MyBiosource	5x500mL	EUR 380

10x Anode buffer
IBS-BA014	iNtRON Biotechnology Inc	500 mL	EUR 66.5

10X Anode buffer
IBS-BA014a	iNtRON Biotechnology Inc	1L	EUR 126.35

10X Tango Buffer
IBS-BT097	iNtRON Biotechnology Inc	10 mL	EUR 28

Permeabilization Buffer (10X)
MBS697331-150mL	MyBiosource	150mL	EUR 175

Permeabilization Buffer (10X)
MBS697331-5x150mL	MyBiosource	5x150mL	EUR 750

Taq Reaction Buffer - Red
abx461046-1096tests	Abbexa	10 × 96 tests	Ask for price

Taq Reaction Buffer - Red
abx461046-596tests	Abbexa	5 × 96 tests	Ask for price

Taq Reaction Buffer - Red
abx461046-96tests	Abbexa	96 tests	EUR 500

Blocking Buffer, 10X, 250ML
X109-250ML	Arbor Assays	250ML	EUR 360

10X Cathode buffer
IBS-BC008	iNtRON Biotechnology Inc	500 mL	EUR 63

10X Cathode buffer
IBS-BC008a	iNtRON Biotechnology Inc	1L	EUR 119.7

10X Loading Buffer
L0503-005	GenDepot	5X1ml	EUR 18

10X Loading Buffer
L0504-005	GenDepot	5X1ml	EUR 18

10X Transfer Buffer
IBS-BT031a	iNtRON Biotechnology Inc	500 mL	EUR 35

10X Transfer Buffer
IBS-BT031b	iNtRON Biotechnology Inc	1L	EUR 66.5

10X Transfer Buffer
ML043-500ML	EWC Diagnostics	1 unit	EUR 12.79
Description: 10X Transfer Buffer

10X Detection Buffer
IBS-BD004	iNtRON Biotechnology Inc	1L	EUR 28

10X Reservoir Buffer
IBS-BR010	iNtRON Biotechnology Inc	1L	EUR 42

DNase I Buffer 10X
10450020-1	Bio-WORLD	1 mL	EUR 25.82

TE Buffer 10X, Tubes
40121082-1	Bio-WORLD	25 mL	Ask for price

TE Buffer 10X, Tubes
40121082-2	Bio-WORLD	50 mL	Ask for price

TAE Buffer - 10x conc.
BU-119-10	Jena Bioscience GmbH	1l	EUR 35.61

TBE Buffer - 10x conc.
BU-120	Jena Bioscience GmbH	1l	EUR 32.21

Restriction Enzyme Buffer for TaqI, 10X
MBS638451-1mL	MyBiosource	1mL	EUR 315

Restriction Enzyme Buffer for TaqI, 10X
MBS638451-5x1mL	MyBiosource	5x1mL	EUR 1270

Taq Reaction Buffer - Colorless
abx461045-1096tests	Abbexa	10 × 96 tests	Ask for price

Taq Reaction Buffer - Colorless
abx461045-596tests	Abbexa	5 × 96 tests	Ask for price

Taq Reaction Buffer - Colorless
abx461045-96tests	Abbexa	96 tests	EUR 437.5

TBE Buffer 10X, Powder
10530018-1	Bio-WORLD	1 L	EUR 62.06

TBE Buffer 10X, Powder
10530018-2	Bio-WORLD	10 L	EUR 165.02

ELISA Wash Buffer, 10X
650	Immunochemistry	100 mL	EUR 44.75

ELISA Wash Buffer, 10X
652	Immunochemistry	1 L	EUR 256

Buffer A 10X, Sterile
40120741-1	Bio-WORLD	100 mL	EUR 21.8

Buffer A 10X, Sterile
40120741-2	Bio-WORLD	500 mL	EUR 45.71

Buffer A 10X, Sterile
40120741-3	Bio-WORLD	1 L	EUR 79.55

RBC Lysing Buffer (10x)
E16FXP001-050	EnoGene	50 tests	EUR 43.33
Description: Available in various conjugation types.

RBC Lysing Buffer (10x)
E16FXP001-100	EnoGene	100 Tests	EUR 73.33
Description: Available in various conjugation types.

RBC Lysing Buffer (10x)
E16FXP001-100ml	EnoGene	100 ml	EUR 98.33
Description: Available in various conjugation types.

RBC Lysing Buffer (10x)
E16FXP001-200ml	EnoGene	200 ml	EUR 160
Description: Available in various conjugation types.

RBC Lysing Buffer (10x)
E16FXP001-500	EnoGene	500 tests	EUR 293.33
Description: Available in various conjugation types.

RBC Lysing Buffer (10x)
E16FXP001-500ml	EnoGene	500 ml	EUR 393.33
Description: Available in various conjugation types.

FOXP3 Perm Buffer (10x)
E16FXP055	EnoGene	25 ml	EUR 260
Description: Available in various conjugation types.

ELISA Wash Buffer, 10X
MBS258403-100mL	MyBiosource	100mL	EUR 150

ELISA Wash Buffer, 10X
MBS258403-1L	MyBiosource	1L	EUR 320

ELISA Wash Buffer, 10X
MBS258403-500mL	MyBiosource	500mL	EUR 225

ELISA Wash Buffer, 10X
MBS258403-5x1L	MyBiosource	5x1L	EUR 1310

Taq Polymerase / Labeling Buffer
PCR-201L	Jena Bioscience GmbH	5x 200units	EUR 174.41
Description: Thermus aquaticus, recombinant, E. coli

Taq Polymerase / Labeling Buffer
PCR-201S	Jena Bioscience GmbH	200units	EUR 43.55
Description: Thermus aquaticus, recombinant, E. coli

IEF Cathode Buffer 10X
10530004-1	Bio-WORLD	250 mL	EUR 48.31

IEF Cathode Buffer 10X
10530004-2	Bio-WORLD	500 mL	EUR 91.56

LPA Buffer 10X, Sterile
40120868-1	Bio-WORLD	10x10 mL	EUR 93.62

Citrare buffer, 10X pH6.0
AR-6544-02	ImmunoBioscience	100ml	EUR 40.6

Citrare buffer, 10X pH6.0
AR-6544-05	ImmunoBioscience	1000ml	EUR 79.65

DNA Loading Buffer (10X)
KDS020	KOMA BIOTECH	2ml	EUR 26
Description: https://komabiotech.co.kr/labiskoma/datasheet/KDS020.pdf

Pfu Reaction Buffer 10X
11170070-1	Bio-WORLD	5x1 ml	EUR 33.33

CAPS Transfer Buffer 10X
20960009-1	Bio-WORLD	100 mL	EUR 31.96
Description: 3- (Cyclohexylamino) -1-propanesulfonic acid, N-Cyclohexyl-3-aminopropanesulfonic acid

CAPS Transfer Buffer 10X
20960009-2	Bio-WORLD	500 mL	EUR 95.76
Description: 3- (Cyclohexylamino) -1-propanesulfonic acid, N-Cyclohexyl-3-aminopropanesulfonic acid

CAPS Transfer Buffer 10X
20960009-3	Bio-WORLD	1 L	EUR 184.16
Description: 3- (Cyclohexylamino) -1-propanesulfonic acid, N-Cyclohexyl-3-aminopropanesulfonic acid

Some fetal tissues (eg, skin, cartilage, tendons, muscles, bones, lungs) can be harvested simultaneously and processed for obedient cell culture, set a unique model for sustainable therapeutic cellular supply chains. Here, we integrate fundamental, preclinical, clinical, and industrial developments to realize scientific progress supported by the Swiss FPC Banking and we focus on progress made for the date of FPC which can be derived from a single organ donation. The new single model of bioprocessing donation is proposed, achieving sustainable standards and potential production of billions of therapeutic doses that are affordable and efficient.