Coronavirus 2019 related disease (Covid-19) became a pandemic in February 2020, and researchers worldwide tried to overcome this disease with drugs agreed to all types, or to develop new compounds that inhibit the spread of the virus. Flavonoids, have been investigated as antivirus in general, can also bear special activities for viral agents that cause […]
Omics tools offer the opportunity to characterize and track traditional food and industrial fermentation. Bioinformatics, through machine learning, and other advanced statistical approaches, able to parse the fermentation process and predict the evolution and metabolic yields of food microbial ecosystems. By assembling a microbial-made consortival, the progress of biotechnology will also be able to increase
Chloroplast biotechnology is a route for new plant metabolic techniques. The potential bio-imprisonment of transgen, high protein expression and the possibility of regulating genes into operons representing a considerable profit that makes valuable target chloroplast in agricultural biotechnology. In the last 3 decades, the chloroplast genome of several economic important plants has been successfully transformed.
BACKGROUNDMelatonin, which is well-known antioxidant, has been shown to have anti-invasive properties for glioma. However, little is known about the effects of melatonin on the migration and invasion of glioma cells under hypoxia, which is essential for the progress of the microenvironment of the tumor. In addition, the focus of adhesion kinase (FAK) and a
BACKGROUND: Modulation of the immune system with a vaccine lymphoma cells genetically modified is a potential therapeutic value in the treatment of B cell lymphoma, however, the anti-tumor effect of single immunogen transfer so far been limited. the combination therapy of recombinant IL-2 and IL-12 have been reported synergistically to stimulate an anti-tumor response in
Asthma is frequently characterized by airway inflammation rich in eosinophils. Airway eosinophilia associated with exacerbations of asthma and may play a part in airway remodeling. Eosinophil recruitment of blood flow depends on the circulation of eosinophils become activated, leading to the arrest on endothelium activated eosinophils, extravasation, and continued movement through the bronchial tissue by
Eosinophil Activation Status in Separate Compartments and Association with Asthma. Read More »
Atherosclerosis is a common chronic inflammatory disease in which angiogenesis is involved. Here we established in vitro cell model of angiogenesis was made by Human dermal microvascular endothelial cells (HMEC-1) and work to investigate the role of triptolide (TPL) in this model. To induce angiogenesis, HMEC-1 cells were cultured on Matrigel-conditioned medium. The ratio of
cell metabolism of lipid, lipoprotein interaction, and liver X receptor (LXR) activation is involved in the pathophysiology and treatment of cancer, although the findings vary in models of cancer and lipoprotein profiles. In this study, we investigated the effects of Human -derived low-density lipoprotein (LDL), high-density lipoprotein (HDL) cholesterol, and HDL-associated protein apolipoprotein A1 (apoA1)
