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Insights from Pharmaceutical Biotechnology into Phenolic Biopharmaceuticals against COVID-19

Insights from Pharmaceutical Biotechnology into Phenolic Biopharmaceuticals against COVID-19

Pandemic Covid-19 has infected more than 3.5 million people worldwide and more than 250 thousand people died in 187 countries in May 2020. Agents because the result of this disease is the Coronavirus that the onset of the symptoms from 6 to 41 days with an average 14 days. This period depends on several factors […]

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Fermented food products in the era of globalization: tradition meets biotechnology innovations

Fermented food products in the era of globalization: tradition meets biotechnology innovations

Omics tools offer the opportunity to characterize and track traditional food and industrial fermentation. Bioinformatics, through machine learning, and other advanced statistical approaches, able to parse the fermentation process and predict the evolution and metabolic yields of food microbial ecosystems. By assembling a microbial-made consortival, the progress of biotechnology will also be able to increase

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Generation, analysis, and transformation of macro-chloroplast Potato (Solanum tuberosum) lines for chloroplast biotechnology

Generation, analysis, and transformation of macro-chloroplast Potato (Solanum tuberosum) lines for chloroplast biotechnology

Chloroplast biotechnology is a route for new plant metabolic techniques. The potential bio-imprisonment of transgen, high protein expression and the possibility of regulating genes into operons representing a considerable profit that makes valuable target chloroplast in agricultural biotechnology. In the last 3 decades, the chloroplast genome of several economic important plants has been successfully transformed.

Generation, analysis, and transformation of macro-chloroplast Potato (Solanum tuberosum) lines for chloroplast biotechnology Read More »

Involvement of ROS-alpha v beta 3 integrin-FAK/Pyk2 in the inhibitory effect of melatonin on U251 glioma cell migration and invasion under hypoxia.

Involvement of ROS-alpha v beta 3 integrin-FAK/Pyk2 in the inhibitory effect of melatonin on U251 glioma cell migration and invasion under hypoxia.

BACKGROUNDMelatonin, which is well-known antioxidant, has been shown to have anti-invasive properties for glioma. However, little is known about the effects of melatonin on the migration and invasion of glioma cells under hypoxia, which is essential for the progress of the microenvironment of the tumor. In addition, the focus of adhesion kinase (FAK) and a

Involvement of ROS-alpha v beta 3 integrin-FAK/Pyk2 in the inhibitory effect of melatonin on U251 glioma cell migration and invasion under hypoxia. Read More »

Effects of recombinant adenovirus-mediated expression of IL-2 and IL-12 in human B lymphoma cells on co-cultured PBMC.

Effects of recombinant adenovirus-mediated expression of IL-2 and IL-12 in human B lymphoma cells on co-cultured PBMC.

BACKGROUND: Modulation of the immune system with a vaccine lymphoma cells genetically modified is a potential therapeutic value in the treatment of B cell lymphoma, however, the anti-tumor effect of single immunogen transfer so far been limited. the combination therapy of recombinant IL-2 and IL-12 have been reported synergistically to stimulate an anti-tumor response in

Effects of recombinant adenovirus-mediated expression of IL-2 and IL-12 in human B lymphoma cells on co-cultured PBMC. Read More »

Eosinophil Activation Status in Separate Compartments and Association with Asthma.

Eosinophil Activation Status in Separate Compartments and Association with Asthma.

Asthma is frequently characterized by airway inflammation rich in eosinophils. Airway eosinophilia associated with exacerbations of asthma and may play a part in airway remodeling. Eosinophil recruitment of blood flow depends on the circulation of eosinophils become activated, leading to the arrest on endothelium activated eosinophils, extravasation, and continued movement through the bronchial tissue by

Eosinophil Activation Status in Separate Compartments and Association with Asthma. Read More »

Triptolide inhibits angiogenesis in microvascular endothelial cells through regulation of miR-92a.

Triptolide inhibits angiogenesis in microvascular endothelial cells through regulation of miR-92a.

Atherosclerosis is a common chronic inflammatory disease in which angiogenesis is involved. Here we established in vitro cell model of angiogenesis was made by Human dermal microvascular endothelial cells (HMEC-1) and work to investigate the role of triptolide (TPL) in this model. To induce angiogenesis, HMEC-1 cells were cultured on Matrigel-conditioned medium. The ratio of

Triptolide inhibits angiogenesis in microvascular endothelial cells through regulation of miR-92a. Read More »

Low-Density Lipoproteins, High-Density Lipoproteins (HDL), and HDL-Associated Proteins Differentially Modulate Chronic Myelogenous Leukemia Cell Viability

Low-Density Lipoproteins, High-Density Lipoproteins (HDL), and HDL-Associated Proteins Differentially Modulate Chronic Myelogenous Leukemia Cell Viability

cell metabolism of lipid, lipoprotein interaction, and liver X receptor (LXR) activation is involved in the pathophysiology and treatment of cancer, although the findings vary in models of cancer and lipoprotein profiles. In this study, we investigated the effects of Human -derived low-density lipoprotein (LDL), high-density lipoprotein (HDL) cholesterol, and HDL-associated protein apolipoprotein A1 (apoA1)

Low-Density Lipoproteins, High-Density Lipoproteins (HDL), and HDL-Associated Proteins Differentially Modulate Chronic Myelogenous Leukemia Cell Viability Read More »